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The Suffolk County Police Department reported that the crash happened shortly after 3 a.m. west of Exit 56 in Hauppauge.
Police said Derrick Louis, age 24, of Westbury, was eastbound in a Nissan Altima when his car struck the back of a Freightliner box truck. The Altima then went off the road into the woods, and then struck a tree.
Louis was taken to Stony Brook University Hospital and was listed in critical condition, according to police.
A 24-year-old woman who was a passenger in the Altima was also treated at the hospital for minor injuries. Police said the 33-year-old man driving the Freightliner was not injured.
The Altima was impounded after the crash for a safety check, and the Freightliner was inspected at the scene, police added.
Investigators are asking anyone with information on the crash to contact the Fourth Squad at 631-854-8452.
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